Peritoneal Equilibration Test (PET) Analysis among Filipino Children on Chronic Peritoneal Dialysis at National Kidney & Transplant Institute
A Cross-Sectional Study
Background. Peritoneal Equilibration Test (PET) is a simple means of characterizing solute transport rates across the peritoneum. It may supply useful information on peritoneal solute transfer characteristics in children on peritoneal dialysis (PD) and facilitate individualized PD prescription.
Objective. To determine the peritoneal membrane characteristics of Filipino children by performing PET to children on chronic peritoneal dialysis, thereby classifying them into low, low- average, high-average and high transport types.
Methods. The study was conducted at the National Kidney and Transplant Institute, Department of Pediatric Nephrology Out-patient Clinic using purposive convenient sampling. A PET was done to each patient. Data analysis was carried out using frequency, percentage distribution, mean and standard deviation in analyzing the demographic characteristics. One-Way Analysis of Variance and Pearson Chi-Square Test/Fisher-Exact Test were used in determining association between PET and possible factors affecting its result at 0.05 level of significance.
Results. A total of 30 pediatric patients on chronic peritoneal dialysis were enrolled. Majority of subjects were predominantly adolescents, with a mean age of 14.3+ 3.196 years old. There were 60% males and 40% females. Chronic glomerulonephritis was the leading cause of ESRD in 83.3%. Seventy seven percent of the population had normal BMI for age and sex percentile, followed by 20% underweight subjects and a case of overweight (3%). PET results revealed 53.3% as low average transporters, 30% as low transporters while 16.7% as high average transporters.
Conclusion. Filipino children on chronic peritoneal dialysis in a specialty center were predominantly classified as low average transporters, followed by low transport type category. There was no significant association between PET type and factors: age, sex, cause of ESRD, weight, height, body surface area (BSA), body mass index (BMI) and duration of dialysis.
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